Antihypertensive Effects and Endothelial Progenitor Cell Activation by Intake of Chicken Collagen Hydrolysate in Pre- and Mild-Hypertension

被引:29
作者
Saiga-Egusa, Ai [1 ]
Iwai, Koji [1 ]
Hayakawa, Toru [1 ]
Takahata, Yoshihisa [1 ]
Morimatsu, Fumiki [1 ]
机构
[1] Nippon Meat Packers Inc, R&D Ctr, Tsukuba, Ibaraki 3002646, Japan
关键词
chicken collagen hydrolysate; hypertension; plasma renin activity; endothelial progenitor cell; ENZYME-INHIBITORY PEPTIDES; CORONARY-ARTERY-DISEASE; PERIPHERAL-BLOOD; BREAST MUSCLE; SENESCENCE; THERAPY;
D O I
10.1271/bbb.80189
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
070307 [化学生物学]; 071010 [生物化学与分子生物学];
摘要
Chicken collagen hydrolysate was given to 15 mildly hypertensive subjects for 4 weeks. Blood pressure was significantly decreased by 11.8 mmHg (P < 0.01). A reduction in plasma renin activity was observed in blood test after intake. A colony assay of endothelial progenitor cells in blood samples from non-smokers revealed an approximately 30% increase in the number of colonies.
引用
收藏
页码:422 / 424
页数:3
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