Antimalarial activity of a new stilbene glycoside from Parthenocissus tricuspidata in mice

被引：38

作者：

Park, Won-Hwan ^{[3
]}

Lee, Sung-Jae ^{[2
]}

Moon, Hyung-In ^{[1
]}

机构：

[1] Wonkwang Univ, Sanbon Med Ctr, Dept Neurol, Inam Neuro Sci Res Ctr, Gunpo City 435040, Kyunggi Do, South Korea

[2] Korea Univ, Coll Med, Dept Integrat Med, Seoul 136705, South Korea

[3] Dongguk Univ, Coll Korean Med, Dept Diagnost & Cardiovasc Med Res Ctr, Gyeong Ju 780714, South Korea

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2008年 / 52卷 / 09期

关键词：

D O I：

10.1128/AAC.00562-08

中图分类号：

Q93 [微生物学];

学科分类号：

071005 [微生物学]; 100705 [微生物与生化药学];

摘要：

A novel stilbene glycoside [piceid-(1 -> 6)-beta-D-glucopyranoside; PBG] from Parthenocissus tricuspidata was tested in vivo against Plasmodium berghei. PBG exhibited significant blood schizontocidal activity in a 4-day early infection, a repository evaluation, and an established infection, with a significant mean survival time comparable to that obtained with the standard drug, chloroquine (5 mg . kg(-1) . day(-1)).

引用

页码：3451 / 3453

页数：3

共 10 条

[1]

BIORJMAN A, 1991, MALARIA WAITING VACC

[2]

In vitro antiplasmodial activity of medicinal plants native to or naturalised in South Africa [J].

Clarkson, C ;

Maharaj, VJ ;

Crouch, NR ;

Grace, WM ;

Pillay, P ;

Matsabisa, MG ;

Bhagwandin, N ;

Smith, PJ ;

Folb, PI .

JOURNAL OF ETHNOPHARMACOLOGY, 2004, 92 (2-3) :177-191

[3]

Antimalarial plants used by Hausa in northern Nigeria [J].

Etkin, NL .

TROPICAL DOCTOR, 1997, 27 :12-16

[4]

INVITRO STUDIES ON THE MODE OF ACTION OF QUASSINOIDS WITH ACTIVITY AGAINST CHLOROQUINE-RESISTANT PLASMODIUM-FALCIPARUM [J].

KIRBY, GC ;

ONEILL, MJ ;

PHILLIPSON, JD ;

WARHURST, DC .

BIOCHEMICAL PHARMACOLOGY, 1989, 38 (24) :4367-4374

[5]

THE ANTI-MALARIAL ACTIVITY OF N-BENZYLOXYDIHYDROTRIAZINES .1. THE ACTIVITY OF CLOCIGUANIL (BRL50216) AGAINST RODENT MALARIA, AND STUDIES ON ITS MODE OF ACTION [J].

KNIGHT, DJ ;

PETERS, W .

ANNALS OF TROPICAL MEDICINE AND PARASITOLOGY, 1980, 74 (04) :393-404

[6]

A NEW APPROACH TO PRACTICAL ACUTE TOXICITY TESTING [J].

LORKE, D .

ARCHIVES OF TOXICOLOGY, 1983, 54 (04) :275-287

[7]

DRUG RESISTANCE IN PLASMODIUM BERGHEI VINCKE AND LIPS 1948 .1. CHLOROQUINE RESISTANCE [J].

PETERS, W .

EXPERIMENTAL PARASITOLOGY, 1965, 17 (01) :80-&

[8]

Ryley J., 1970, AM J TROP MED PARASI, V84, P209

[9]

Antiplasmodial activity of novel stilbene derivatives isolated from Parthenocissus tricuspidata from South Korea [J].

Son, Il Hong ;

Chung, Ill-Min ;

Lee, Sun-Joo ;

Moon, Hyung-In .

PARASITOLOGY RESEARCH, 2007, 101 (01) :237-241

[10]

TRAGER W, 1976, SCIENCE, V193, P673, DOI 10.1126/science.781840

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