Diffraction phase microscopy for quantifying cell structure and dynamics

被引：726

作者：

Popescu, G

Ikeda, T

Dasari, RR

Feld, MS

机构：

[1] MIT, George R Harrison Spect Lab, Cambridge, MA 02139 USA

[2] Hamamatsu Photon KK, Hamamatsu, Shizuoka 4348601, Japan

来源：

OPTICS LETTERS | 2006年 / 31卷 / 06期

关键词：

D O I：

10.1364/OL.31.000775

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

We have developed diffraction phase microscopy as a new technique for quantitative phase imaging of biological structures. The method combines the principles of common path interferometry and single-shot phase imaging and is characterized by subnanometer path-length stability and millisecond-scale acquisition time. The potential of the technique for quantifying nanoseale motions in live cells is demonstrated by experiments on red blood cells. (c) 2006 Optical Society of America.

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收藏

页码：775 / 777

页数：3

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