Uncovered: The family relationship of a T-cell-membrane protein and bacterial toxins

被引：33

作者：

KochNolte, F ^{[1
]}

Haag, F ^{[1
]}

Kastelein, R ^{[1
]}

Bazan, F ^{[1
]}

机构：

[1] DNAX RES INST MOL & CELLULAR BIOL INC,PALO ALTO,CA 94304

来源：

IMMUNOLOGY TODAY | 1996年 / 17卷 / 09期

关键词：

D O I：

10.1016/0167-5699(96)30023-6

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Mono-ADP-ribosylation was originally discovered as the mechanism by which diphtheria toxin inactivates protein synthesis. It is now apparent that higher organisms use analogous mechanisms to regulate endogenous metabolism. Here, the relationship between bacterial toxins and vertebrate mono-ADP ribosyltransferases is explored.

引用

页码：402 / 405

页数：4

共 30 条

[1] COMMON FEATURES OF THE NAD-BINDING AND CATALYTIC SITE OF ADP-RIBOSYLATING TOXINS
DOMENIGHINI, M
MAGAGNOLI, C
PIZZA, M
RAPPUOLI, R
[J]. MOLECULAR MICROBIOLOGY, 1994, 14 (01) : 41 - 50
[2] EVIDENCE THAT THE T-CELL REPERTOIRE OF NORMAL RATS CONTAINS CELLS WITH THE POTENTIAL TO CAUSE DIABETES - CHARACTERIZATION OF THE CD4+ T-CELL SUBSET THAT INHIBITS THIS AUTOIMMUNE POTENTIAL
FOWELL, D
MASON, D
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1993, 177 (03) : 627 - 636
[3] FRA AM, 1994, J BIOL CHEM, V269, P30745
[4] DEPLETION OF RT6.1+ LYMPHOCYTES-T INDUCES DIABETES IN RESISTANT BIOBREEDING WORCESTER (BB/W) RATS
GREINER, DL
MORDES, JP
HANDLER, ES
ANGELILLO, M
NAKAMURA, N
ROSSINI, AA
[J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1987, 166 (02) : 461 - 475
[5] BOTH ALLELIC FORMS OF THE RAT T-CELL DIFFERENTIATION MARKER RT6 DISPLAY NICOTINAMIDE ADENINE-DINUCLEOTIDE (NAD)-GLYCOHYDROLASE ACTIVITY, YET ONLY RT6.2 IS CAPABLE OF AUTOMODIFICATION UPON INCUBATION WITH NAD
HAAG, F
ANDRESEN, V
KARSTEN, S
KOCHNOLTE, F
THIELE, HG
[J]. EUROPEAN JOURNAL OF IMMUNOLOGY, 1995, 25 (08) : 2355 - 2361
[6] PREMATURE STOP CODONS INACTIVATE THE RT6 GENES OF THE HUMAN AND CHIMPANZEE SPECIES
HAAG, F
KOCHNOLTE, F
KUHL, M
LORENZEN, S
THIELE, HG
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1994, 243 (03) : 537 - 546
[7] PRIMARY STRUCTURE OF RAT RT6.2, A NONGLYCOSYLATED PHOSPHATIDYLINOSITOL-LINKED SURFACE MARKER OF POSTTHYMIC T-CELLS
KOCH, F
HAAG, F
KASHAN, A
THIELE, HG
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1990, 87 (03) : 964 - 967
[8] DEFECTS IN THE STRUCTURE AND EXPRESSION OF THE GENES FOR THE T-CELL MARKER RT6 IN NZW AND (NZBXNZW)F1 MICE
KOCHNOLTE, F
KLEIN, J
HOLLMANN, C
KUHL, M
HAAG, F
GASKINS, HR
LEITER, E
THIELE, HG
[J]. INTERNATIONAL IMMUNOLOGY, 1995, 7 (05) : 883 - 890
[9] Mouse T cell membrane proteins Rt6-1 and Rt6-2 are arginine protein mono(ADPribosyl)transferases and share secondary structure motifs with ADP-ribosylating bacterial toxins
KochNolte, F
Petersen, D
Balasubramanian, S
Haag, F
Kahlke, D
Willer, T
Kastelein, R
Bazan, F
Thiele, HG
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (13) : 7686 - 7693
[10] KOCHNOLTE F, 1995, IMMUNOGENETICS, V41, P152, DOI 10.1007/BF00182329

← 1 2 3 →