Ultrasound-guided skeletal biopsies

Objective: Percutaneous biopsy of skeletal lesions is a widely used diagnostic technique that involves fluoroscopic or computerized tomography guidance. The objective of this report is to describe the use of ultrasonography in the guidance of percutaneous biopsy of skeletal lesions. Design and patients: We employed ultrasound to guide percutaneous biopsy in 65 skeletal lesions in 63 patients (30 male and 33 female) whose ages ranged from 1 to 82 years (mean 47.2 years). The lesions were divided into four groups: group 1 (n=41) were lytic with a soft tissue mass, group 2 (n=14) were lytic with a disrupted cortex without a soft tissue mass, group 3 (n=4) were lytic with an intact cortex and group 4 (n=6) were sclerotic lesions. Different techniques and materials were used in each group. Results: Cytologic assessment obtained the diagnosis in 50 cases, (success rate 76.9%), histology in 56 cases (86.1%) and a combination of both in 60 cases (92.3%). There were no complications. Conclusions: Ultrasound is a highly accurate and safe method of guidance in percutaneous biopsy of bone lesions, either lytic or sclerotic, because it can identify subtle changes in the cortical and the associated soft tissue component.