Individualized surgical strategy for the reduction of stroke risk in patients undergoing coronary artery bypass grafting

被引:28
作者
Gaudino, M
Glieca, F
Alessandrini, F
Cellini, C
Luciani, N
Pragliola, C
Schiavello, R
Possati, G
机构
[1] Catholic Univ, Dept Cardiac Surg, Rome, Italy
[2] Catholic Univ, Dept Anesthesiol, Rome, Italy
关键词
D O I
10.1016/S0003-4975(99)00151-4
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background. This study was designed to evaluate the efficacy of a protocol of systematic screening of the ascending aorta and internal carotid arteries and individualization of the surgical strategy to the ascending aorta and internal carotid arteries status in reducing the stroke incidence among patients undergoing coronary artery bypass grafting. Methods. On the basis of a pre- and intraoperative screening of the ascending aorta and internal carotid arteries, 2,326 consecutive patients undergoing coronary artery bypass grafting were divided in low, moderate, and high neurologic risk groups. In the high-risk group dedicated surgical techniques were always adopted and the reduction of the neurologic risk tvas considered more important than the achievement of total revascularization. Results. The incidence of perioperative stroke in the high-risk group was similar to those of the other two groups (1.1 versus 1.3 and 1.1%, respectively; p = not significant); however, angina recurrence was significantly more frequent in the high-risk group. Conclusions. The described strategy allows a low rate of perioperative stroke in high-risk patients undergoing coronary artery bypass grafting. Whether the reduction of the neurologic risk outweighs the benefits of complete revascularization remains to be determined. (Ann Thorac Surg 1999;67:1246-53) (C) 1999 by The Society of Thoracic Surgeons.
引用
收藏
页码:1246 / 1253
页数:8
相关论文
共 19 条
[1]  
BARZILAI B, 1989, CIRCULATION, V80, P275
[2]   MYOCARDIAL REVASCULARIZATION WITHOUT EXTRACORPOREAL-CIRCULATION - 7 YEAR EXPERIENCE IN 593 CASES [J].
BUFFOLO, E ;
ANDRADE, JCS ;
BRANCO, JNR ;
AGUIAR, LF ;
RIBEIRO, EE ;
JATENE, AD .
EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 1990, 4 (09) :504-508
[3]   STROKE FOLLOWING CORONARY-ARTERY BYPASS-GRAFTING - A 10-YEAR STUDY [J].
GARDNER, TJ ;
HORNEFFER, PJ ;
MANOLIO, TA ;
PEARSON, TA ;
GOTT, VL ;
BAUMGARTNER, WA ;
BORKON, AM ;
WATKINS, L ;
REITZ, BA .
ANNALS OF THORACIC SURGERY, 1985, 40 (06) :574-581
[4]   A CRITICAL-ASSESSMENT OF NEUROLOGICAL RISK DURING WARM HEART-SURGERY [J].
GUYTON, RA ;
MELLITT, RJ ;
WEINTRAUB, WS .
JOURNAL OF CARDIAC SURGERY, 1995, 10 (04) :488-492
[5]  
JENNETT B, 1975, LANCET, V1, P480
[6]   PROTRUDING AORTIC ATHEROMAS PREDICT STROKE IN ELDERLY PATIENTS UNDERGOING CARDIOPULMONARY BYPASS - EXPERIENCE WITH INTRAOPERATIVE TRANSESOPHAGEAL ECHOCARDIOGRAPHY [J].
KATZ, ES ;
TUNICK, PA ;
RUSINEK, H ;
RIBAKOVE, G ;
SPENCER, FC ;
KRONZON, I .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1992, 20 (01) :70-77
[7]   RISK-FACTORS FOR STROKE AFTER CORONARY-ARTERY BYPASS [J].
LYNN, GM ;
STEFANKO, K ;
REED, JF ;
GEE, W ;
NICHOLAS, G .
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 1992, 104 (06) :1518-1523
[8]   PROSPECTIVE, RANDOMIZED TRIAL OF RETROGRADE WARM BLOOD CARDIOPLEGIA - MYOCARDIAL BENEFIT AND NEUROLOGIC THREAT [J].
MARTIN, TD ;
CRAVER, JM ;
GOTT, JP ;
WEINTRAUB, WS ;
RAMSAY, J ;
MORA, CT ;
GUYTON, RA .
ANNALS OF THORACIC SURGERY, 1994, 57 (02) :298-304
[9]  
McKhann GM, 1997, ANN THORAC SURG, V63, P516
[10]   Risk factors for stroke in patients undergoing coronary artery bypass grafting [J].
Mickleborough, LL ;
Walker, PM ;
Takagi, Y ;
Ohashi, M ;
Ivanov, J ;
Tamariz, M .
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 1996, 112 (05) :1250-1258