The pathogenesis of immune thrombocytopaenic purpura

被引：202

作者：

Cooper, N ^{[1
]}

Bussel, J ^{[1
]}

机构：

[1] Cornell Univ, Weill Med Coll, Dept Pediat, New York, NY 10021 USA

来源：

BRITISH JOURNAL OF HAEMATOLOGY | 2006年 / 133卷 / 04期

关键词：

thrombocytopaenia; immune thrombocytopaenic purpura; pathology; T cells; cytokines;

D O I：

10.1111/j.1365-2141.2006.06024.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Immune thrombocytopaenic purpura (ITP) is an autoimmune bleeding disease that is rarely fatal. However, in many adults treatment is unsatisfactory, with as much morbidity from the immunosuppressive effects of treatment as from bleeding. Identifying the underlying disease process should help us to identify more targeted therapies and improve not only the treatment but also the quality of life of patients with this disorder.

引用

页码：364 / 374

页数：11