Voltammetric determination of nitric oxide on cobalt phthalocyanine modified microelectrodes

被引：58

作者：

Vilakazi, SL ^{[1
]}

Nyokong, T ^{[1
]}

机构：

[1] Rhodes Univ, Dept Chem, ZA-6140 Grahamstown, South Africa

来源：

JOURNAL OF ELECTROANALYTICAL CHEMISTRY | 2001年 / 512卷 / 1-2期

基金：

新加坡国家研究基金会;

关键词：

cobalt phthalocyanine; nitric oxide; electrocatalysis; microelectrode; dopamine; serotonin;

D O I：

10.1016/S0022-0728(01)00583-6

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The catalytic activity of a carbon fiber microelectrode modified with cobalt phthalocyanine (CoPc-ME) for the detection of nitric oxide in the presence of possible interfering molecules (dopamine and serotonin) is examined. A linear plot is observed for the variation of the catalytic currents with NO concentration in the presence of excess dopamine and serotonin, showing that NO may be determined in the presence of these molecules. However, oxidation currents due to serotonin were found to decrease with increase in NO concentration. The CoPc-ME could also detect NO added to blood or its components, the oxidation currents for NO, however, decreased rapidly with time. The decrease in currents was slower in blood serum, followed by whole blood, with a faster decrease being observed in blood plasma. (C) 2001 Elsevier Science BN. All rights reserved.

引用

页码：56 / 63

页数：8

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