Soft Tissue Sarcoma, Version 2.2012 Featured Updates to the NCCN Guidelines

被引：104

作者：

von Mehren, Margaret ^{[1
]}

Benjamin, Robert S. ^{[2
]}

Bui, Marilyn M. ^{[3
]}

Casper, Ephraim S. ^{[4
]}

Conrad, Ernest U., III ^{[5
]}

DeLaney, Thomas F. ^{[6
]}

Ganjoo, Kristen N. ^{[7
]}

George, Suzanne

Gonzalez, Ricardo ^{[3
]}

Heslin, Martin J. ^{[8
]}

Kane, John M., III ^{[9
]}

Mayerson, Joel ^{[10
]}

McGarry, Sean V. ^{[11
]}

Meyer, Christian ^{[12
]}

O'Donnell, Richard J. ^{[13
]}

Paz, I. Benjamin ^{[14
]}

Pfeifer, John D. ^{[15
,16
]}

Pollock, Raphael E. ^{[2
]}

Randall, R. Lor ^{[17
]}

Riedel, Richard F.

Schuetze, Scott ^{[18
]}

Schupak, Karen D. ^{[4
]}

Schwartz, Herbert S. ^{[19
]}

Shankar, Sridhar ^{[20
]}

Van Tine, Brian A. ^{[15
,16
]}

Wayne, Jeffrey ^{[21
]}

Sundar, Hema

McMillian, Nicole R.

机构：

[1] Fox Chase Canc Ctr, Philadelphia, PA 19111 USA

[2] Univ Texas MD Anderson Canc Ctr, Houston, TX USA

[3] H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL USA

[4] Mem Sloan Kettering Canc Ctr, New York, NY USA

[5] Seattle Canc Care Alliance, Fred Hutchinson Canc Res Ctr, Seattle, WA USA

[6] Massachusetts Gen Hosp, Ctr Canc, Boston, MA 02114 USA

[7] Stanford Canc Inst, Stanford, CA USA

[8] Univ Alabama Birmingham, Ctr Comprehens Canc, Birmingham, AL USA

[9] Roswell Pk Canc Inst, Buffalo, NY USA

[10] Ohio State Univ, Ctr Comprehens Canc, James Canc Hosp, Columbus, OH 43210 USA

[11] Nebraska Med Ctr, UNMC Eppley Canc Ctr, Omaha, NE USA

[12] Johns Hopkins, Sidney Kimmel Comprehens Canc Ctr, Baltimore, MD USA

[13] Univ Calif San Francisco, Helen Diller Family Comprehens Canc Ctr, San Francisco, CA 94143 USA

[14] City Hope Comprehens Canc Ctr, Duarte, CA USA

[15] Barnes Jewish Hosp, Siteman Canc Ctr, St Louis, MO USA

[16] Washington Univ, Sch Med, St Louis, MO 63130 USA

[17] Univ Utah, Huntsman Canc Inst, Salt Lake City, UT 84112 USA

[18] Univ Michigan, Ctr Comprehens Canc, Ann Arbor, MI 48109 USA

[19] Vanderbilt Ingram Canc Ctr, Nashville, TN USA

[20] Univ Tennessee, Inst Canc, St Jude Childrens Res Hosp, Knoxville, TN 37996 USA

[21] Northwestern Univ, Robert H Lurie Comprehens Canc Ctr, Evanston, IL 60208 USA

来源：

JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK | 2012年 / 10卷 / 08期

关键词：

GASTROINTESTINAL STROMAL TUMORS; OF-FUNCTION MUTATIONS; PHASE-II TRIAL; IMATINIB MESYLATE; PROGNOSTIC-FACTORS; ADJUVANT IMATINIB; DESMOID TUMOR; GIST; KIT; FIBROMATOSIS;

D O I：

10.6004/jnccn.2012.0099

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

The major changes to the 2012 and 2011 NCCN Guidelines for Soft Tissue Sarcoma pertain to the management of patients with gastrointestinal stromal tumors (GISTs) and desmoid tumors (aggressive fibromatosis). Postoperative imatinib following complete resection for primary GIST with no preoperative imatinib is now included as a category 1 recommendation for patients with intermediate or high risk of recurrence. The panel also reaffirmed the recommendation for preoperative use of imatinib in patients with GISTs that are resectable with negative margins but associated with significant surgical morbidity. Observation was included as an option for patients with resectable desmoid tumors that are small and asymptomatic, not causing morbidity, pain, or functional limitation. Sorafenib is included as an option for systemic therapy for patients with desmoid tumors. (JNCCN 2012;10:951-960)

引用

页码：951 / 960

页数：10

共 30 条

[1]

[Anonymous], 2010, J CONTRACEPT FERTIL, V28, P1247

[2]

Desmoid tumor: Prognostic factors and outcome after surgery, radiation therapy, or combined surgery and radiation therapy [J].

Ballo, MT ;

Zagars, GK ;

Pollack, A ;

Pisters, PWT ;

Pollock, RA .

JOURNAL OF CLINICAL ONCOLOGY, 1999, 17 (01) :158-167

[3]

Long-term results from a randomized phase II trial of standard- versus higher-dose imatinib mesylate for patients with unresectable or metastatic gastrointestinal stromal tumors expressing KIT [J].

Blanke, Charles D. ;

Demetri, George D. ;

von Mehren, Margaret ;

Heinrich, Michael C. ;

Eisenberg, Burton ;

Fletcher, Jonathan A. ;

Corless, Christopher L. ;

Fletcher, Christopher D. M. ;

Roberts, Peter J. ;

Heinz, Daniela ;

Wehre, Elisabeth ;

Nikolova, Zariana ;

Joensuu, Heikki .

JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (04) :620-625

[4]

Neoadjuvant imatinib in patients with locally advanced non metastatic GIST in the prospective BFR14 trial [J].

Blesius, Aurore ;

Cassier, Philippe A. ;

Bertucci, Francois ;

Fayette, Jerome ;

Ray-Coquard, Isabelle ;

Bui, Binh ;

Adenis, Antoine ;

Rios, Maria ;

Cupissol, Didier ;

Perol, David ;

Blay, Jean-Yves ;

Le Cesne, Axel .

BMC CANCER, 2011, 11

[5]

Extra-abdominal primary fibromatosis:: Aggressive management could be avoided in a subgroup of patients [J].

Bonvalot, S. ;

Eldweny, H. ;

Haddad, V. ;

Rimareix, F. ;

Missenard, G. ;

Oberlin, O. ;

Vanel, D. ;

Terrier, P. ;

Blay, J. Y. ;

Le Cesne, A. ;

Le Pechoux, C. .

EJSO, 2008, 34 (04) :462-468

[6]

KIT mutations and dose selection for imatinib in patients with advanced gastrointestinal stromal tumours [J].

Debiec-Rychter, Maria ;

Sciot, Raf ;

Le Cesne, Axel ;

Schlemmer, Marcus ;

Hohenberger, Peter ;

van Oosterom, Allan T. ;

Blay, Jean-Yves ;

Leyvraz, Serge ;

Stul, Michel ;

Casali, Paolo G. ;

Zalcberg, John ;

Verweij, Jaap ;

Van Glabbeke, Martine ;

Hagemeijer, Anne ;

Judson, Ian .

EUROPEAN JOURNAL OF CANCER, 2006, 42 (08) :1093-1103

[7]

Adjuvant imatinib mesylate after resection of localised, primary gastrointestinal stromal tumour: a randomised, double-blind, placebo-controlled trial [J].

DeMatteo, Ronald P. ;

Ballman, Karla V. ;

Antonescu, Cristina R. ;

Maki, Robert G. ;

Pisters, Peter W. T. ;

Demetri, George D. ;

Blackstein, Martin E. ;

Blanke, Charles D. ;

von Mehren, Margaret ;

Brennan, Murray F. ;

Patel, Shreyaskumar ;

McCarter, Martin D. ;

Polikoff, Jonathan A. ;

Tan, Benjamin R. ;

Owzar, Kouros .

LANCET, 2009, 373 (9669) :1097-1104

[8]

Two hundred gastrointestinal stromal tumors - Recurrence patterns and prognostic factors for survival [J].

DeMatteo, RP ;

Lewis, JJ ;

Leung, D ;

Mudan, SS ;

Woodruff, JM ;

Brennan, MF .

ANNALS OF SURGERY, 2000, 231 (01) :51-58

[9]

Dematteo RP, 2005, J CLIN ONCOL S1, V23

[10]

Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors [J].

Demetri, GD ;

von Mehren, M ;

Blanke, CD ;

Van den Abbeele, AD ;

Eisenberg, B ;

Roberts, PJ ;

Heinrich, MC ;

Tuveson, DA ;

Singer, S ;

Janicek, M ;

Fletcher, JA ;

Silverman, SG ;

Silberman, SL ;

Capdeville, R ;

Kiese, B ;

Peng, B ;

Dimitrijevic, S ;

Druker, BJ ;

Corless, C ;

Fletcher, CDM ;

Joensuu, H .

NEW ENGLAND JOURNAL OF MEDICINE, 2002, 347 (07) :472-480

← 1 2 3 →