Effects of Yoku-kan-san-ka-chimpi-hange on the sleep of normal healthy adult subjects

被引：43

作者：

Aizawa, R ^{[1
]}

Kanbayashi, T

Saito, Y

Ogawa, Y

Sugiyama, T

Kitajima, T

Kaneko, Y

Abe, M

Shimizu, T

机构：

[1] Japanese Red Cross Jr Coll Akita, Akita 0101406, Japan

[2] Akita Univ, Sch Med, Dept Psychiat, Akita 010, Japan

[3] Fujita Hlth Univ, Sch Med, Dept Psychiat, Toyoake, Aichi 47011, Japan

来源：

PSYCHIATRY AND CLINICAL NEUROSCIENCES | 2002年 / 56卷 / 03期

关键词：

electroencephalogram; herbal medicine; human; polysomnography; Yoku-kan-san-ka-chimpi-hange;

D O I：

10.1046/j.1440-1819.2002.01006.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Yoku-kan-san-ka-chimpi-hange (YKCH) is a drug used for insomnia in Japanese traditional herbal medicine. The present study evaluated the effects of YKCH on sleep by all-night polysomnography using the double-blind method. Yoku-kan-san-ka-chimpi-hange increased the total sleep time significantly, and tended to cause an increase in sleep efficiency and of stage 2 sleep, as well as a decrease of sleep latency and of stage 3 + 4 sleep. There was no apparent influence on rapid eye movement (REM) sleep. In terms of non-REM sleep, the effects of YKCH exhibit a profile similar to those of benzodiazepines.

引用

页码：303 / 304

页数：2