Forty-Five Years of Marburg Virus Research

被引：156

作者：

Brauburger, Kristina

Hume, Adam J.

Muehlberger, Elke ^{[1
]}

Olejnik, Judith

机构：

[1] Boston Univ, Sch Med, Dept Microbiol, Boston, MA 02118 USA

来源：

VIRUSES-BASEL | 2012年 / 4卷 / 10期

基金：

美国国家卫生研究院;

关键词：

Marburg virus; filoviruses; epidemiology; ecology; clinical manifestations; virus structure; replication cycle; pathogenesis; animal models; vaccine development; SANS-FRONTIERES INTERVENTION; HEMORRHAGIC-FEVER EPIDEMIC; LINKED-IMMUNOSORBENT-ASSAY; PROTECTS NONHUMAN-PRIMATES; I INTERFERON RESPONSE; FOLATE RECEPTOR-ALPHA; EBOLA-VIRUS; MATRIX PROTEIN; GUINEA-PIGS; ZAIRE-EBOLAVIRUS;

D O I：

10.3390/v4101878

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

In 1967, the first reported filovirus hemorrhagic fever outbreak took place in Germany and the former Yugoslavia. The causative agent that was identified during this outbreak, Marburg virus, is one of the most deadly human pathogens. This article provides a comprehensive overview of our current knowledge about Marburg virus disease ranging from ecology to pathogenesis and molecular biology.

引用

页码：1878 / 1927

页数：50

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