17β-Hydroxysteroid dehydrogenase (HSD)/17-ketosteroid reductase (KSR) family;: nomenclature and main characteristics of the 17HSD/KSR enzymes

被引:259
作者
Peltoketo, H [1 ]
Luu-The, V
Simard, J
Adamski, J
机构
[1] Univ Oulu, Bioctr Oulu, FIN-90220 Oulu, Finland
[2] Univ Oulu, WHO Collaborating Ctr Res Reprod Hlth, FIN-90220 Oulu, Finland
[3] CHUL Res Ctr, MRC, Grp Mol Endocrinol, Quebec City, PQ, Canada
[4] Univ Laval, Quebec City, PQ, Canada
[5] GSF, Natl Res Ctr hlth & Environm, Inst Mammalian Genet, Genome Anal Ctr, Neuherberg, Germany
关键词
D O I
10.1677/jme.0.0230001
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A number of enzymes possessing 17 beta-hydroxysteroid dehydrogenase/17-ketosteroid reductase (17HSD/KSR) activities have been described and cloned, but their nomenclature needs specification. To clarify the present situation, descriptions of the eight cloned 17HSD/KSRs are given and guidelines for the classification of novel 17HSD/KSR enzymes are presented.
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页码:1 / 11
页数:11
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