Efficient copper-free PdCl2(PCy3)2-catalyzed Sonogashira coupling of aryl chlorides with terminal alkynes

被引：143

作者：

Yi, CY ^{[1
]}

Hua, RM ^{[1
]}

机构：

[1] Tsinghua Univ, Dept Chem, Innovat Catalysis Program, Key Lab Organ Optoelect & Mol Engn,Minist Educ, Beijing 100084, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2006年 / 71卷 / 06期

关键词：

D O I：

10.1021/jo0525175

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Under copper-free conditions and with Cs2CO3 as a base, PdCl2(PCy3)(2) showed high catalytic activity for cross-coupling of electron-rich, electron-neutral, and electron-deficient aryl chlorides with a variety of terminal alkynes in DMSO at 100-120 degrees C affording internal arylated alkynes in good to excellent yields.

引用

页码：2535 / 2537

页数：3

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