An aye for eye gene therapy

被引:13
作者
Bennett, J [1 ]
机构
[1] Univ Penn, Scheie Eye Inst, FM Kirby Ctr Mol Ophthalmol, Philadelphia, PA 19104 USA
关键词
D O I
10.1089/hum.2006.17.177
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
引用
收藏
页码:177 / 179
页数:3
相关论文
共 25 条
[1]   Long-term restoration of rod and cone vision by single dose rAAV-mediated gene transfer to the retina in a canine model of childhood blindness [J].
Acland, GM ;
Aguirre, GD ;
Bennett, J ;
Aleman, TS ;
Cideciyan, AV ;
Bennicelli, J ;
Dejneka, NS ;
Pearce-Kelling, SE ;
Maguire, AM ;
Palczewski, K ;
Hauswirth, WW ;
Jacobson, SG .
MOLECULAR THERAPY, 2005, 12 (06) :1072-1082
[2]   Gene therapy restores vision in a canine model of childhood blindness [J].
Acland, GM ;
Aguirre, GD ;
Ray, J ;
Zhang, Q ;
Aleman, TS ;
Cideciyan, AV ;
Pearce-Kelling, SE ;
Anand, V ;
Zeng, Y ;
Maguire, AM ;
Jacobson, SG ;
Hauswirth, WW ;
Bennett, J .
NATURE GENETICS, 2001, 28 (01) :92-95
[3]   Co-injection of adenovirus expressing CTLA4-Ig prolongs adenovirally mediated lacZ reporter gene expression in the mouse retina [J].
Ali, RR ;
Reichel, MB ;
Byrnes, AP ;
Stephens, CJ ;
Thrasher, AJ ;
Baker, D ;
Hunt, DM ;
Bhattacharya, SS .
GENE THERAPY, 1998, 5 (11) :1561-1565
[4]   Exchange of surface proteins impacts on viral vector cellular specificity and transduction characteristics: the retina as a model [J].
Auricchio, A ;
Kobinger, G ;
Anand, V ;
Hildinger, M ;
O'Connor, E ;
Maguire, AM ;
Wilson, JM ;
Bennett, J .
HUMAN MOLECULAR GENETICS, 2001, 10 (26) :3075-3081
[5]   Photoreceptor cell rescue in retinal degeneration (rd) mice by in vivo gene therapy [J].
Bennett, J ;
Tanabe, T ;
Sun, DX ;
Zeng, Y ;
Kjeldbye, H ;
Gouras, P ;
Maguire, AM .
NATURE MEDICINE, 1996, 2 (06) :649-654
[6]  
BENNETT J, 1994, INVEST OPHTH VIS SCI, V35, P2535
[7]  
BENNETT J, 1999, TOPIC FOCUS RECOMBIN
[8]   Adenoviral vector-delivered pigment epithelium-derived factor for neovascular age-related macular degeneration: Results of a phase I clinical trial [J].
Campochiaro, PA ;
Nguyen, QD ;
Shah, SM ;
Klein, ML ;
Holz, E ;
Frank, RN ;
Saperstein, DA ;
Gupta, A ;
Stout, JT ;
Macko, J ;
DiBartolomeo, R ;
Wei, LL .
HUMAN GENE THERAPY, 2006, 17 (02) :167-176
[9]   Response of retinoblastoma with vitreous tumor seeding to adenovirus-mediated delivery of thymidine kinase followed by ganciclovir [J].
Chévez-Barrios, P ;
Chintagumpala, M ;
Mieler, W ;
Paysse, E ;
Boniuk, M ;
Kozinetz, C ;
Hurwitz, MY ;
Hurwitz, RL .
JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (31) :7927-7935
[10]   In utero gene therapy rescues vision in a murine model of congenital blindness [J].
Dejneka, NS ;
Surace, EM ;
Aleman, TS ;
Cideciyan, AV ;
Lyubarsky, A ;
Savchenko, A ;
Redmond, TM ;
Tang, WX ;
Wei, ZY ;
Rex, TS ;
Glover, E ;
Maguire, AM ;
Pugh, EN ;
Jacobson, SG ;
Bennett, J .
MOLECULAR THERAPY, 2004, 9 (02) :182-188