Malignant migrating partial seizures of infancy controlled by stiripentol and clonazepam

被引：27

作者：

Merdariu, Dana ^{[1
]}

Delanoe, Catherine ^{[2
]}

Mahfoufi, Nora ^{[3
]}

Bellavoine, Vanina ^{[1
]}

Auvin, Stephane ^{[1
,4
,5
]}

机构：

[1] Hop Robert Debre, APHP, Serv Neurol Pediat, F-75019 Paris, France

[2] Hop Robert Debre, APHP, Serv Explorat Fonct, F-75019 Paris, France

[3] Hop Jean de la Fontaine, Serv Pediat, St Denis, France

[4] INSERM U676, Paris, France

[5] Univ Paris Diderot, INSERM UMR676, Paris, France

来源：

BRAIN & DEVELOPMENT | 2013年 / 35卷 / 02期

关键词：

Antiepileptic drugs; Seizure; Malignant migrating partial seizure of infancy; Epilepsy; Infants; EPILEPSY;

D O I：

10.1016/j.braindev.2012.03.016

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The syndrome of malignant migrating partial seizures of infancy (MMPSI) is characterized by early onset of multiple seizure types and overall poor prognosis. Seizures are markedly drug resistant and few reports have suggested the efficacy of some antiepileptic drugs. We report one case of MMPSI in which prolonged seizure control is obtained with an association of clonazepam, levetiracetam and stiripentol, confirming thus the possibility of complete sustained seizure control in this epileptic syndrome. Of more than 60 cases reported to date, ours is the forth in which sustained complete control of seizures was obtained. (C) 2012 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.

引用

页码：177 / 180

页数：4

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