Hepatitis B and C virus infection in Polish children with malignancies

被引：11

作者：

Januszkiewicz, D ^{[1
]}

Wysocki, J ^{[1
]}

Nowak, J ^{[1
]}

机构：

[1] ACAD MED SCI,INST PAEDIAT,POZNAN,POLAND

来源：

EUROPEAN JOURNAL OF PEDIATRICS | 1997年 / 156卷 / 06期

关键词：

hepatitis B and C virus; malignancies in children; passive immunization against HBV infection;

D O I：

10.1007/s004310050637

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Infections by hepatotropic viruses belong to the most common complications of chemotherapy in children suffering from neoplastic diseases. The rate of hepatitis B virus (HBV) or hepatitis C virus (HCV) infection and the effectiveness of passive immunization against HBV were studied in 285 children; 148/285 with lymphoproliferative diseases and 137/285 with solid tumours. HBV infection was observed in 10.2% children receiving hepatitis B immune globulin as compared to 36.8% without passive immunization against HBV. Anti-HCV antibodies were similar in both groups amounting 38.7% and 32.6% respectively. Conclusion The results show that hepatitis B immune globulin administration is effective and that HCV might become the main cause of hepatitis among immunosuppressed patients in the future.

引用

页码：454 / 456

页数：3

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