Severity assessment criteria recommended by the British Thoracic Society (BTS) for community-acquired pneumonia (CAP) and older patients. Should SOAR (systolic blood pressure, oxygenation, age and respiratory rate) criteria be used in older people? A compilation study of two prospective cohorts

被引:97
作者
Myint, PK
Kamath, AV
Vowler, SL
Maisey, DN
Harrison, BDW
机构
[1] Norfolk & Norwich Univ Hosp, Dept Med Elderly, Norwich NR4 7UY, Norfolk, England
[2] Univ E Anglia, Sch Med Hlth Policy & Pract, Norwich NR4 7TJ, Norfolk, England
[3] Univ Cambridge, Addenbrookes Hosp, Dept Publ Hlth & Primary Care, Clin Gerontol Unit, Cambridge CB2 2QQ, England
[4] Norfolk & Norwich Univ Hosp, Dept Resp Med, Norwich NR4 7UY, Norfolk, England
[5] Univ Cambridge, Dept Publ Hlth & Primary Care, Ctr Appl Med Stat, Cambridge CB2 2SR, England
关键词
BTS guidelines; community-acquired pneumonia (CAP); mortality; older people; elderly;
D O I
10.1093/ageing/afj081
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Objectives: to assess the usefulness of the British Thoracic Society guidelines for severity assessment of community-acquired pneumonia (CAP) in predicting mortality and to explore alternative criteria which could be more useful in older patients. Design: compilation study of two prospective observational cohorts. Setting and participants: a university hospital in Norfolk, UK with a catchment population of 568,000. Subjects were 195 patients (median age = 77 years) who were included in two prospective studies of CAP. Main outcome measure: all-cause mortality occurring within the 6 week follow-up. Results: sensitivity, specificity, positive and negative predictive values for study outcome using CURB and CURB-65 were assessed in 189 patients, and CRB-65 in 192 patients out of a total of 195 patients. Our results were comparable with the original study by Lim et al. Although CURB-65 and CRB-65 included age criteria, in effect they did not materially improve the specificity in predicting high-risk patients in both studies. We found that oxygenation measured by ventilation perfusion mismatch (PaO2:FiO(2)) was the best predictor of outcome in this slightly older cohort [odds ratio (OR) = 0.99 (0.98-0.99), P = 0.0001]. We derived a new set of criteria; SOAR (systolic blood pressure, oxygenation, age and respiratory rate) based on our findings. Their sensitivity, specificity, positive and negative predictive values were 81.0% (58.1-94.6), 59.3% (49.6-68.4), 27.0% (16.6-39.7) and 94.4% (86.2-98.4), respectively, confirming their comparability with existing criteria. Conclusions: our study confirms the usefulness of currently recommended severity rules for CAP in this older cohort. SOAR criteria may be useful as alternative criteria for a better identification of severe CAP in advanced age where both raised urea level above 7 mmol/l and confusion are common.
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页码:286 / 291
页数:6
相关论文
共 21 条
[1]  
ANDREWS BE, 1987, Q J MED, V62, P195
[2]  
Bartlett John G., 2000, Clinical Infectious Diseases, V31, P347, DOI 10.1086/313954
[3]   SURVIVAL AFTER CARDIOPULMONARY RESUSCITATION IN THE HOSPITAL [J].
BEDELL, SE ;
DELBANCO, TL ;
COOK, EF ;
EPSTEIN, FH .
NEW ENGLAND JOURNAL OF MEDICINE, 1983, 309 (10) :569-576
[4]   Severe community-acquired pneumonia - Assessment of severity criteria [J].
Ewig, S ;
Ruiz, M ;
Mensa, J ;
Marcos, MA ;
Martinez, JA ;
Arancibia, F ;
Niederman, MS ;
Torres, A .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1998, 158 (04) :1102-1108
[5]   PREDICTING DEATH IN PATIENTS HOSPITALIZED FOR COMMUNITY-ACQUIRED PNEUMONIA [J].
FARR, BM ;
SLOMAN, AJ ;
FISCH, MJ .
ANNALS OF INTERNAL MEDICINE, 1991, 115 (06) :428-436
[6]  
FINCH R, 1993, BRIT J HOSP MED, V49, P346
[7]   A prediction rule to identify low-risk patients with community-acquired pneumonia [J].
Fine, MJ ;
Auble, TE ;
Yealy, DM ;
Hanusa, BH ;
Weissfeld, LA ;
Singer, DE ;
Coley, CM ;
Marrie, TJ ;
Kapoor, WN .
NEW ENGLAND JOURNAL OF MEDICINE, 1997, 336 (04) :243-250
[8]  
HODKINSON HM, 1976, COMMON SYMPTOMS DISE, P24
[9]   Community-acquired pneumonia in older patients [J].
Janssens, JP ;
Gauthey, L ;
Herrmann, F ;
Tkatch, L ;
Michel, JP .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 1996, 44 (05) :539-544
[10]   Recognising severe pneumonia with simple clinical and biochemical measurements [J].
Kamath, A ;
Pasteur, MC ;
Slade, MG ;
Harrison, BDW .
CLINICAL MEDICINE, 2003, 3 (01) :54-56