A pilot trial of quetiapine for the treatment of patients with delirium

被引:51
作者
Pae, CU [1 ]
Lee, SJ [1 ]
Lee, CU [1 ]
Lee, C [1 ]
Paik, IH [1 ]
机构
[1] Catholic Univ Korea, Kangnam St Marys Hosp, Dept Psychiat, Coll Med, Seoul 137701, South Korea
关键词
quetiapine; delirium; delirium rating scale-revised-98; clinical global impression scale; Korean;
D O I
10.1002/hup.559
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Twenty-two Korean inpatients with delirium were administered prospectively a flexible dose of quetiapine. The delirium rating scale-revised-severity 98 (DRS-R-98) and clinical global impression scale-severity (CGI-s) scores were assessed at the time of pre- and post-treatment. The DRS-R-98 and CGI-s scores were significantly reduced by 57.3% and 55.1%, respectively. Quetiapine was effective and safe for the treatment of patients with delirium, and could be a useful alternative agent to classical antipsychotics in the treatment of delirium. Copyright (C) 2004 John Wiley Sons, Ltd.
引用
收藏
页码:125 / 127
页数:3
相关论文
共 13 条
[1]   Quetiapine for treatment-resistant delirium [J].
Al-Samarrai, S ;
Dunn, J ;
Newmark, T ;
Gupta, S .
PSYCHOSOMATICS, 2003, 44 (04) :350-351
[2]   An open trial of olanzapine for the treatment of delirium in hospitalized cancer patients [J].
Breitbart, W ;
Tremblay, A ;
Gibson, C .
PSYCHOSOMATICS, 2002, 43 (03) :175-182
[3]  
Guy W, 1976, ECDEU assessment manual for psychopharmacology, P223
[4]   Treatment for delirium with risperidone: results of a prospective open trial with 10 patients [J].
Horikawa, N ;
Yamazaki, T ;
Miyamoto, K ;
Kurosawa, A ;
Oiso, H ;
Matsumoto, F ;
Nishimura, K ;
Karasawa, K ;
Takamatsu, K .
GENERAL HOSPITAL PSYCHIATRY, 2003, 25 (04) :289-292
[5]   An open pilot trial of olanzapine for delirium in the Korean population [J].
Kim, KS ;
Pae, CU ;
Chae, JH ;
Bahk, WM ;
Jun, T .
PSYCHIATRY AND CLINICAL NEUROSCIENCES, 2001, 55 (05) :515-519
[6]   Treatment of delirium in older adults with quetiapine [J].
Kim, KY ;
Bader, GM ;
Kotlyar, V ;
Gropper, D .
JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY, 2003, 16 (01) :29-31
[7]   Diagnostic and Statistical Manual of Mental Disorders [J].
Mittal, Vijay A. ;
Walker, Elaine F. .
PSYCHIATRY RESEARCH, 2011, 189 (01) :158-159
[8]   The role of atypical antipsychotics in the treatment of delirium [J].
Schwartz, TL ;
Masand, PS .
PSYCHOSOMATICS, 2002, 43 (03) :171-174
[9]  
SCHWARTZ TL, 2000, J CLIN PSYCHIAT PRIM, V2, P10
[10]  
Sim FH, 2000, CAN J PSYCHIAT, V45, P299