Predictive factors for metachronous recurrence of early gastric cancer after endoscopic treatment

被引:41
作者
Arima, N [1 ]
Adachi, K [1 ]
Katsube, T [1 ]
Amano, K [1 ]
Ishihara, S [1 ]
Watanabe, M [1 ]
Kinoshita, Y [1 ]
机构
[1] Shimane Med Univ, Dept Internal Med 2, Izumo, Shimane 6938501, Japan
关键词
early gastric cancer; endoscopic treatment; metachronous recurrence; Helicobacter pylori infection; synchronous multiple lesions;
D O I
10.1097/00004836-199907000-00011
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Since endoscopic treatment has been evaluated and become established as treatment for early gastric cancer, metachronous recurrence has become a major problem. In this report, predictive factors for recurrence were studied using the Kaplan-Meier method and Cox's proportional hazards regression model in 76 patients who received endoscopic treatment. There were 48 men and 28 women age 69.6 +/- 8.3 years (mean +/- standard deviation), 5 of whom had synchronous multiple lesions and 71 who had a single lesion found during the initial endoscopic treatment. In all patients, periodic follow-ups were performed by endoscopy for more than 2 years after treatment. Helicobacter pylori infection was assessed in 55 of the 76 patients, and proved positive in 43 and negative in 12. Metachronous recurrence was detected significantly more frequently in patients whose synchronous multiple lesions were found during the initial treatment. In addition, age affected the recurrence positively. However, Sender and H. pylori infection had no significant relationship with metachronous recurrence.
引用
收藏
页码:44 / 47
页数:4
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