Multiple atypical adenomatous hyperplasia with synchronous multiple primary bronchioloalveolar carcinomas

被引:9
作者
Kishi, K [1 ]
Homma, S [1 ]
Kurosaki, A [1 ]
Tanaka, S [1 ]
Matsushita, H [1 ]
Nakata, K [1 ]
机构
[1] Toranomon Gen Hosp, Div Resp Div, Minato Ku, Tokyo 1058470, Japan
关键词
AAH; BAC; ground glass attenuation; high resolution computed tomography;
D O I
10.2169/internalmedicine.41.474
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We report a case of multiple atypical adenomatous hyperplasia (AAH) associated with synchronous multiple primary bronchioloalveolar carcinomas (BACs). A 58-year-old man was visited for bronchial asthma. A chest computed tomography (CT) scan revealed small, multiple nodules with ground glass attenuation (GGA) throughout both lungs, predominantly in the upper lobes. A high resolution CT (HRCT) scan disclosed well-defined nodules with uniform GGA. Thoracoscopic wedge lung biopsy confirmed the diagnosis. The patient was treated with chemotherapy and had stable disease for two years. It is important to recognize that multiple AAH associated with multiple BACs can present as diffuse, well-defined nodules with uniform GGA on HRCT.
引用
收藏
页码:474 / 477
页数:4
相关论文
共 18 条
[1]   A case of double primary adenocarcinoma of the lung with multiple atypical adenomatous hyperplasia [J].
Anami, Y ;
Matsuno, Y ;
Yamada, T ;
Takeuchi, T ;
Nakayama, H ;
Hirohashi, S ;
Noguchi, M .
PATHOLOGY INTERNATIONAL, 1998, 48 (08) :634-640
[2]   The association between atypical adenomatous hyperplasia and primary lung cancer [J].
Chapman, AD ;
Kerr, KM .
BRITISH JOURNAL OF CANCER, 2000, 83 (05) :632-636
[3]   Synchronous four primary lung adenocarcinoma associated with multiple atypical adenomatous hyperplasia [J].
Dohmoto, K ;
Fujita, J ;
Ohtsuki, Y ;
Kotsuna, N ;
Mitsunaka, H ;
Kuwabara, H ;
Takahara, J .
LUNG CANCER, 2000, 27 (02) :125-130
[4]  
Kitamura H, 1999, AM J CLIN PATHOL, V111, P610
[5]   BRONCHIOLOALVEOLAR ADENOMA OF THE LUNG - CT-PATHOLOGICAL CORRELATION [J].
KUSHIHASHI, T ;
MUNECHIKA, H ;
RI, K ;
KUBOTA, H ;
UKISU, R ;
SATOH, S ;
MOTOYA, H ;
KURASHITA, Y ;
SOEJIMA, K ;
KADOKURA, M ;
HISHIDA, T .
RADIOLOGY, 1994, 193 (03) :789-793
[6]  
MARTINI N, 1975, J THORAC CARDIOV SUR, V70, P606
[7]  
MILLER RR, 1988, CANCER-AM CANCER SOC, V61, P1009, DOI 10.1002/1097-0142(19880301)61:5<1009::AID-CNCR2820610525>3.0.CO
[8]  
2-L
[9]   BRONCHIOLOALVEOLAR CELL ADENOMAS [J].
MILLER, RR .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1990, 14 (10) :904-912
[10]   Micronodular pneumocyte hyperplasia [J].
Muir, TE ;
Leslie, KO ;
Popper, H ;
Kitaichi, M ;
Gagné, E ;
Emelin, JK ;
Vinters, HV ;
Colby, TV .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1998, 22 (04) :465-472