ATP synthase: two motors, two fuels

被引:50
作者
Oster, G [1 ]
Wang, HY
机构
[1] Univ Calif Berkeley, Coll Nat Resources, Dept Mol, Berkeley, CA 94720 USA
[2] Univ Calif Berkeley, Coll Nat Resources, Dept Cellular Biol, Berkeley, CA 94720 USA
基金
美国国家科学基金会;
关键词
D O I
10.1016/S0969-2126(99)80046-X
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
F0F1 ATPase is the universal protein responsible for ATP synthesis. The enzyme comprises two reversible rotary motors: F-0 is either an ion 'turbine' or an ion pump, and F-1 is either a hydrolysis motor or an ATP synthesizer. Recent biophysical and biochemical studies have helped to elucidate the operating principles for both motors.
引用
收藏
页码:R67 / R72
页数:6
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