Toxicological analysis of sulpiride in a lethal poisoning case

被引:17
作者
Rop, PP [1 ]
Sournac, MH [1 ]
Elie, I [1 ]
Burle, J [1 ]
Fornaris, M [1 ]
机构
[1] Lab Police Sci Marseille, F-13248 Marseille 04, France
关键词
D O I
10.1093/jat/23.4.294
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
A fatality following ingestion of sulpiride is presented. The drug was identified and quantitated in postmortem blood by gas chromatography-mass spectrometry and high-performance liquid chromatography with diode-array detection. The concentration was 38 μg/mL, which was in excess of 34 times the therapeutic concentration of sulpiride. For other associated drugs, their concentrations were in their therapeutic ranges.
引用
收藏
页码:294 / 296
页数:3
相关论文
共 14 条
[1]  
BRON J, 1987, J PHARM BELG, V42, P47
[2]  
CORVOL P, 1974, SEM HOP PARIS, V50, P1265
[3]  
Darmanaden R., 1992, Journal de Pharmacie Clinique, V11, P306
[4]  
DUFFIELD AD, 1990, TIAFT B, V20, P9
[5]  
GAULTIER M, 1973, Journal Europeen de Toxicologie, V6, P42
[6]  
JENER P, 1981, NEUROPHARMACOLOGY, V20, P1285
[7]  
KINTZ P, 1994, TIAFT B, V24, P37
[8]  
MONTAZ L, 1992, J TOXICOL CLIN EXPER, V12, P481
[9]  
SEGERBERGKONTTINEN M, 1989, J FORENSIC SCI, V34, P500
[10]  
SUGNAUX FR, 1978, EUR J DRUG METAB PH, V4, P235