Obesity and cardiovascular disease - Pathophysiology, evaluation, and effect of weight loss

被引：578

作者：

Poirier, P ^{[1
]}

Giles, TD ^{[1
]}

Bray, GA ^{[1
]}

Hong, YL ^{[1
]}

Stern, JS ^{[1
]}

Pi-Sunyer, FX ^{[1
]}

Eckel, RH ^{[1
]}

机构：

[1] Quebec Heart & Lund Inst, Ste Foy, PQ G1V 4G5, Canada

来源：

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY | 2006年 / 26卷 / 05期

关键词：

congestive heart failure; myocardial biology; structure;

D O I：

10.1161/01.ATV.0000216787.85457.f3

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Obesity is becoming a global epidemic in both children and adults, and it is associated with numerous co-morbidities such as cardiovascular diseases (CVD), type 2 diabetes, hypertension, certain cancers, and sleep apnea/sleep-disordered breathing. In fact, is an independent risk factor for CVD and CVD risks have been also documented in obese children, and is associated with reduced life expectancy. A variety of adaptations/alterations in cardiac structure and function occur in the individual as adipose tissue accumulates in excess amount. As a whole, overweight/obesity predispose or is associated with numerous cardiac complications such as coronary heart disease, heart failure, and sudden death through its impact on the cardiovascular system.

引用

页码：968 / 976

页数：9

共 161 条

[1] BODY MASS INDEX AND THROMBOEMBOLIC STROKE IN NONSMOKING MEN IN OLDER MIDDLE-AGE - THE HONOLULU-HEART-PROGRAM [J].