This article provides an overview of an open source qualitative coding and analysis program called TAMS Analyzer, where TANIS stands for Text Analysis Mark-up System. The article reviews the history and design of this software. This history focuses on transformations in the software that have allowed it to work with larger scale projects, more abstract analytic categories, and wider varieties of media. In examining the software design, the article reflects variously on the value of software-assisted qualitative research, issues of openness with respect to software standards and licensing, and transparency to the user. It concludes by looking at some future directions for software-assisted qualitative research and by noting contradictions in the qualitative marketplace that will likely shape what will be available to qualitative researchers.