A Direct Palladium-Catalyzed Route to Selectively Substituted Carbazoles through Sequential C-C and C-N Bond Formation: Synthesis of Carbazomycin A

被引：78

作者：

Della Ca, Nicola ^{[1
,2
]}

Sassi, Giovanni ^{[1
,2
]}

Catellani, Marta ^{[1
,2
]}

机构：

[1] Univ Parma, Dipartimento Chim Organ & Ind, I-43100 Parma, Italy

[2] Univ Parma, CIRCC, I-43100 Parma, Italy

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2008年 / 350卷 / 14-15期

关键词：

carbazoles; catalysis; C-H activation; norbornene; palladium;

D O I：

10.1002/adsc.200800421

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The present paper offers a synthetically simple one-pot procedure for the catalytic preparation of the biologically interesting class of carbazoles. The new procedure is based on the combined catalysis of palladium and norbornene starting from o-substituted iodoarenes and N-sulfonylated or N-acetylated o-bromoanilines. A well-known member of this class, carbazomycin A, has been successfully prepared.

引用

页码：2179 / 2182

页数：4

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