Cold and warm denaturation of proteins

被引：35

作者：

Caldarelli, G

De Los Rios, P

机构：

[1] Univ Roma La Sapienza, Dipartimento Fis, I-00185 Rome, Italy

[2] INFM, Sez Roma 1, I-00185 Rome, Italy

[3] Univ Lausanne, Inst Phys Theor, CH-1015 Lausanne, Switzerland

来源：

JOURNAL OF BIOLOGICAL PHYSICS | 2001年 / 27卷 / 2-3期

关键词：

cold denaturation; hydrophobic forces; proteins;

D O I：

10.1023/A:1013145009949

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

We introduce a simplified protein model where the water degrees of freedom appear explicitly (although in an extremely simplified fashion). Using this model we are able to recover both the warm and the cold protein denaturation within a single framework, while addressing important issues about the structure of model proteins.

引用

页码：229 / 241

页数：13

共 34 条

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