Episodic activation of the coagulation system in unstable angina does not elicit an acute phase reaction

This study investigated the temporal relation between activation of the coagulation system and the inflammatory system in unstable angina, and demonstrates that episodic activation of the coagulation system, although common in this syndrome, does not, by itself, represent a sufficiently strong stimulus to determine an increase in plasma levels of the acute phase reactant, C-reactive protein. Our study suggests that the acute phase response observed in unstable angina may be related to a primary inflammatory component.