Design and semisynthesis of spermine-sensitive ribonuclease S

被引：9

作者：

Hamachi, I ^{[1
]}

Yamada, Y ^{[1
]}

Eboshi, R ^{[1
]}

Hiraoka, T ^{[1
]}

Shinkai, S ^{[1
]}

机构：

[1] Kyushu Univ, Grad Sch Engn, Dept Chem & Biochem, Fukuoka 8128581, Japan

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1999年 / 9卷 / 09期

关键词：

D O I：

10.1016/S0960-894X(99)00189-4

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Spermine-sensitive stabilization of semisynthetic Ribonuclease S' was successfully carried out by sequence specific incorporation of a poly-anion domain into alpha-helix region of S-peptide. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：1215 / 1218

页数：4

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