Molecular mechanisms of vertebrate photoreceptor light adaptation

被引:266
作者
Pugh, EN
Nikonov, S
Lamb, TD
机构
[1] Univ Penn, Dept Ophthalmol, FM Kirby Ctr Mol Ophthalmol, Philadelphia, PA 19104 USA
[2] Univ Penn, Inst Neurol Sci, Stellar Chance Labs, Philadelphia, PA 19104 USA
[3] Univ Cambridge, Dept Physiol, Cambridge CB2 3EG, England
基金
英国惠康基金;
关键词
D O I
10.1016/S0959-4388(99)80062-2
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
An important recent advance in the understanding of vertebrate photoreceptor light adaptation has come from the discovery that as many as eight distinct molecular mechanisms may be involved, and the realization that one of the principal mechanisms is not dependent on calcium. Quantitative analysis of these mechanisms is providing new insights into the nature of rod photoreceptor light adaptation.
引用
收藏
页码:410 / 418
页数:9
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