High frequencies of CYP2C19 mutations and poor metabolism of proguanil in Vanuatu

被引：37

作者：

Kaneko, A

Kaneko, O

Taleo, G

Bjorkman, A

Kobayakawa, T

机构：

[1] OSAKA CITY UNIV,SCH MED,DEPT MED ZOOL,OSAKA 545,JAPAN

[2] DEPT HLTH,MALARIA SECT,PORT VILA,VANUATU

[3] KAROLINSKA INST,DANDERYD HOSP,DIV INFECT DIS,STOCKHOLM,SWEDEN

来源：

LANCET | 1997年 / 349卷 / 9056期

关键词：

D O I：

10.1016/S0140-6736(05)62696-7

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

收藏

页码：921 / 922

页数：2

相关论文

共 5 条

[1] GEOGRAPHICAL INTERRACIAL DIFFERENCES IN POLYMORPHIC DRUG OXIDATION - CURRENT STATE OF KNOWLEDGE OF CYTOCHROMES P450 (CYP) 2D6 AND 2C19
BERTILSSON, L
[J]. CLINICAL PHARMACOKINETICS, 1995, 29 (03) : 192 - 209
[2] DEMORAIS SMF, 1994, MOL PHARMACOL, V46, P594
[3] KATAYAMA K, 1990, MAN CULTURE OCEANIA, V6, P151
[4] Atovaquone and proguanil for Plasmodium falciparum malaria
Radloff, PD
Philipps, J
Nkeyi, M
Hutchinson, D
Kremsner, PG
[J]. LANCET, 1996, 347 (9014) : 1511 - 1514
[5] THE ACTIVATION OF THE BIGUANIDE ANTIMALARIAL PROGUANIL CO-SEGREGATES WITH THE MEPHENYTOIN OXIDATION POLYMORPHISM - A PANEL STUDY
WARD, SA
HELSBY, NA
SKJELBO, E
BROSEN, K
GRAM, LF
BRECKENRIDGE, AM
[J]. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1991, 31 (06) : 689 - 692