Anti-androgens for the treatment of hirsutism

被引：17

作者：

Carmina, E ^{[1
]}

机构：

[1] Univ Palermo, Dept Clin Med, I-90139 Palermo, Italy

来源：

EXPERT OPINION ON INVESTIGATIONAL DRUGS | 2002年 / 11卷 / 03期

关键词：

anti-androgens; hirsutism; idiopathic hirsutism; polycystic ovary syndrome;

D O I：

10.1517/13543784.11.3.357

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Many alternatives exist for treating hirsutism. Based on an analysis of scientific literature and on the experiences of the author, the most common antiandrogen agents are discussed in this review. Androgen receptor blockers (cyproterone acetate, flutamide and spironolactone), 5alpha-reductase inhibitors (finasteride) and androgen-suppressing agents (gonadotrophin-releasing hormone [GnRH] agonists, oestroprogestins, corticosteroids and insulin-sensitising agents) are evaluated and compared. The importance of diagnosis in choosing the most appropriate anti-androgen treatment is also discussed.

引用

收藏

页码：357 / 363

页数：7

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