Quantitative detection of serum HBV DNA in Chinese patients

被引：1

作者：

Lai, VCH

Lai, CL

Low, BG

Lau, JYN

Wu, PC

机构：

[1] UNIV HONG KONG,DEPT PATHOL,HONG KONG,HONG KONG

[2] UNIV HONG KONG,DEPT MED,HONG KONG,HONG KONG

[3] UNIV FLORIDA,SECT HEPATOBILIARY DIS,GAINESVILLE,FL

来源：

JOURNAL OF VIRAL HEPATITIS | 1997年 / 4卷 / 05期

关键词：

assay; Chinese; chronic hepatitis B; HBeAg; HBV; HBV DNA; quantification;

D O I：

10.1046/j.1365-2893.1997.00058.x

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The relationship between serum hepatitis Be antigen (HBeAg) and serum hepatitis B virus (HBV) DNA determined by two commercially available assays was examined in 345 Chinese patients with chronic HBV infection. HBV DNA was detected by these commercial assays in 85% of the HBeAg-positive patients. Discrepancies between test results were found to occur when serum HBV DNA levels were low (<5 pg ml(-1) for the Abbott Genostics and <100MEq ml(-1) for Chiron Quantiplex assays). An equation for the conversion between results generated by these two assays was derived, which was found to be very similar to the equation recently described by Kapke et al.

引用

页码：359 / 362

页数：4

共 7 条

[1]

HENDRICKS DA, 1995, AM J CLIN PATHOL, V104, P537

[2]

RAPID AND SENSITIVE METHOD FOR THE DETECTION OF SERUM HEPATITIS-B VIRUS-DNA USING THE POLYMERASE CHAIN-REACTION TECHNIQUE [J].