MascotDatfile: An open-source library to fully parse and analyse MASCOT MS/MS search results

被引：41

作者：

Helsens, Kenny

Martens, Lennart

Vandekerckhove, Joel

Gevaert, Kris

机构：

[1] European Bioinformat Inst, EMBL Outstn, Cambridge, England

[2] Univ Ghent VIB, Dept Biochem & Med Prot Res, Fac Med & Hlth Sci, Ghent, Belgium

来源：

PROTEOMICS | 2007年 / 7卷 / 03期

关键词：

bioinformatics; protein identification;

D O I：

10.1002/pmic.200600682

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

MS-based protein identification is an important part of both gel-based and gel-free proteome studies. The MASCOT search engine (http://www.matrixscience.com) provides one of the most popular automated algorithms for this task. Here we present an open-source software library written in Java that parses raw MASCOT results into an easily accessible and fully functional object model (http://genesis.ugent.be/MascotDatfile). Several scripts based on this library are provided as examples, allowing direct automation of important routine tasks involved in processing peptide identifications.

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收藏

页码：364 / 366

页数：3

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