Synthesis of allocolchicines using sequential ring-closing enyne metathesis-Diels-Alder reactions

被引：44

作者：

Boyer, Francois-Didier ^{[1
]}

Hanna, Issam

机构：

[1] INRA, Unite Chim Biol, F-78026 Versailles, France

[2] Ecole Polytech, CNRS, Organ Synth Lab, F-91128 Palaiseau, France

来源：

ORGANIC LETTERS | 2007年 / 9卷 / 04期

关键词：

D O I：

10.1021/ol0630548

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

New allocolchinoids having functionality in the C ring at position C10 or C11 have been synthesized using the enyne ring-closing metathesis (RCM) reaction for construction of the seven-membered ring and a Diels-Alder-aromatization sequence for the elaboration of the aromatic ring C.

引用

页码：715 / 718

页数：4

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