QuickTree: building huge Neighbour-Joining trees of protein sequences

被引:216
作者
Howe, K [1 ]
Bateman, A [1 ]
Durbin, R [1 ]
机构
[1] Wellcome Trust Sanger Inst, Hinxton CB10 1SA, England
关键词
D O I
10.1093/bioinformatics/18.11.1546
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
We have written a fast implementation of the popular Neighbor-Joining tree building algorithm. QuickTree allows the reconstruction of phylogenies for very large protein families (including the largest Pfam alignment containing 27000 HIV GP120 glycoprotein sequences) that would be infeasible using other popular methods.
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页码:1546 / 1547
页数:2
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