Nonvariceal upper gastrointestinal bleeding: Standard and new treatment

被引:22
作者
Ferguson, CB [1 ]
Mitchell, RM [1 ]
机构
[1] Belfast City Hosp, Dept Gastroenterol, Belfast BT9 7AB, Antrim, North Ireland
关键词
D O I
10.1016/j.gtc.2005.08.003
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Nonvariceal upper gastrointestinal bleeding remains a challenging problem with a significant morbidity and mortality. In recent years endoscopic techniques have evolved, resulting in improved primary hemostasis and a reduction in the risk of rebleeding. Combination endoscopic therapy followed by high-dose proton pump inhibitor shows improved outcomes. Innovative endoscopic therapies hold promise but are as yet unproved. An aging population with significant medical comorbidities has a major influence on the overall outcome from upper gastrointestinal bleeding.
引用
收藏
页码:607 / +
页数:16
相关论文
共 89 条
[1]   Nasogastric aspirate predicts high-risk endoscopic lesions in patients with acute upper-GI bleeding [J].
Aljebreen, AM ;
Fallone, CA ;
Barkun, AN .
GASTROINTESTINAL ENDOSCOPY, 2004, 59 (02) :172-178
[2]   Efficacy of endoscopic pure ethanol injection method for gastrointestinal ulcer bleeding [J].
Asaki, S .
WORLD JOURNAL OF SURGERY, 2000, 24 (03) :294-298
[3]   ENDOSCOPIC HEMOSTASIS BY LOCAL INJECTION OF EPINEPHRINE AND POLIDOCANOL IN BLEEDING ULCER - A PROSPECTIVE RANDOMIZED TRIAL [J].
BALANZO, J ;
SAINZ, S ;
SUCH, J ;
ESPINOS, JC ;
GUARNER, C ;
CUSSO, X ;
MONES, J ;
VILARDELL, F .
ENDOSCOPY, 1988, 20 (06) :289-291
[4]   CIMETIDINE AND TRANEXAMIC ACID IN THE TREATMENT OF ACUTE UPPER-GASTROINTESTINAL-TRACT BLEEDING [J].
BARER, D ;
OGILVIE, A ;
HENRY, D ;
DRONFIELD, M ;
COGGON, D ;
FRENCH, S ;
ELLIS, S ;
ATKINSON, M ;
LANGMAN, M .
NEW ENGLAND JOURNAL OF MEDICINE, 1983, 308 (26) :1571-1575
[5]   Consensus recommendations for managing patients with nonvariceal upper gastrointestinal bleeding [J].
Barkun, A ;
Bardou, M ;
Marshall, JK .
ANNALS OF INTERNAL MEDICINE, 2003, 139 (10) :843-857
[6]   The Canadian Registry on nonvariceal Upper Gastrointestinal Bleeding and Endoscopy (RUGBE): Endoscopic hemostasis and proton pump inhibition are associated with improved outcomes in a real-life setting [J].
Barkun, A ;
Sabbah, S ;
Enns, R ;
Armstrong, D ;
Gregor, J ;
Fedorak, RN ;
Rahme, E ;
Toubouti, Y ;
Martel, M ;
Chiba, N ;
Fallone, CA .
AMERICAN JOURNAL OF GASTROENTEROLOGY, 2004, 99 (07) :1238-1246
[7]   SUPERGLUE - THE ANSWER TO VARICEAL BLEEDING AND FUNDAL VARICES [J].
BINMOELLER, KF ;
SOEHENDRA, N .
ENDOSCOPY, 1995, 27 (05) :392-396
[8]   A risk score to predict need for treatment for upper-gastrointestinal haemorrhage [J].
Blatchford, O ;
Murray, WR ;
Blatchford, M .
LANCET, 2000, 356 (9238) :1318-1321
[9]   The frequency of peptic ulcer as a cause of upper-GI bleeding is exaggerated [J].
Boonpongmanee, S ;
Fleischer, DE ;
Pezzullo, JC ;
Collier, K ;
Mayoral, W ;
Al-Kawas, F ;
Chutkan, R ;
Lewis, JH ;
Tio, TL ;
Benjamin, SB .
GASTROINTESTINAL ENDOSCOPY, 2004, 59 (07) :788-794
[10]   IMPORTANCE OF HYPOVOLEMIC SHOCK AND ENDOSCOPIC SIGNS IN PREDICTING RECURRENT HEMORRHAGE FROM PEPTIC-ULCERATION - A PROSPECTIVE EVALUATION [J].
BORNMAN, PC ;
THEODOROU, NA ;
SHUTTLEWORTH, RD ;
ESSEL, HP ;
MARKS, IN .
BRITISH MEDICAL JOURNAL, 1985, 291 (6490) :245-247