Epoxide hydrolases: Structure, function, mechanism, and assay

被引：82

作者：

Arand, M ^{[1
]}

Cronin, A

Adamska, M

Oesch, F

机构：

[1] Univ Wurzburg, Inst Pharmakol & Toxikol, Wurzburg, Germany

[2] Johannes Gutenberg Univ Mainz, Inst Toxikol, Mainz, Germany

来源：

PHASE II CONJUGATION ENZYMES AND TRANSPORT SYSTEMS | 2005年 / 400卷

关键词：

D O I：

10.1016/S0076-6879(05)00032-7

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Epoxide hydrolases are a class of enzymes important in the detoxification of genotoxic compounds, as well as in the control of physiological signaling molecules. This chapter gives an overview on the function, structure, and enzymatic mechanism of structurally characterized epoxide hydrolases and describes selected assays for the quantification of epoxide hydrolase activity.

引用

页码：569 / 588

页数：20

共 69 条

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