Clinical interest of KRAS mutation detection in blood for anti-EGFR therapies in metastatic colorectal cancer

被引:29
作者
Di Fiore, F. [1 ,2 ]
Charbonnier, F. [1 ]
Lefebure, B. [1 ,3 ]
Laurent, M. [4 ]
Le Pessot, F. [1 ,4 ]
Michel, P. [1 ,2 ]
Frebourg, T. [1 ]
机构
[1] INSERM, U614, Fac Med, Inst Biomed Res, Rouen, France
[2] Univ Hosp, Digest Oncol Unit, Dept Hepatogastroenterol, Rouen, France
[3] Univ Hosp, Dept Surg, Rouen, France
[4] Univ Hosp, Dept Pathol, Rouen, France
关键词
D O I
10.1038/sj.bjc.6604451
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:551 / 552
页数:2
相关论文
共 9 条
[1]   Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer [J].
Amado, Rafael G. ;
Wolf, Michael ;
Peeters, Marc ;
Van Cutsem, Eric ;
Siena, Salvatore ;
Freeman, Daniel J. ;
Juan, Todd ;
Sikorski, Robert ;
Suggs, Sid ;
Radinsky, Robert ;
Patterson, Scott D. ;
Chang, David D. .
JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (10) :1626-1634
[2]   Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies [J].
Benvenuti, Silvia ;
Sartore-Bianchi, Andrea ;
Di Nicolantonio, Federica ;
Zanon, Carlo ;
Moroni, Mauro ;
Veronese, Silvio ;
Siena, Salvatore ;
Bardelli, Alberto .
CANCER RESEARCH, 2007, 67 (06) :2643-2648
[3]   KRAS wild-type state predicts survival and is associated to early radiological response in metastatic colorectal cancer treated with cetuximab [J].
De Roock, W. ;
Piessevaux, H. ;
De Schutter, J. ;
Janssens, M. ;
De Hertogh, G. ;
Personeni, N. ;
Biesmans, B. ;
Van Laethem, J. -L. ;
Peeters, M. ;
Humblet, Y. ;
Van Cutsem, E. ;
Tejpar, S. .
ANNALS OF ONCOLOGY, 2008, 19 (03) :508-515
[4]   Clinical relevance of KRAS mutation detection in metastatic colorectal cancer treated by Cetuximab plus chemotherapy [J].
Di Fiore, F. ;
Blanchard, F. ;
Charbonnier, F. ;
Le Pessot, F. ;
Lamy, A. ;
Galais, M. P. ;
Bastit, L. ;
Killian, A. ;
Sesboue, R. ;
Tuech, J. J. ;
Queuniet, A. M. ;
Paillot, B. ;
Sabourin, J. C. ;
Michot, F. ;
Michel, P. ;
Frebourg, T. .
BRITISH JOURNAL OF CANCER, 2007, 96 (08) :1166-1169
[5]   PTEN loss of expression predicts cetuximab efficacy in metastatic colorectal cancer patients [J].
Frattini, M. ;
Saletti, P. ;
Romagnani, E. ;
Martin, V. ;
Molinari, F. ;
Ghisletta, M. ;
Camponovo, A. ;
Etienne, L. L. ;
Cavalli, F. ;
Mazzucchelli, L. .
BRITISH JOURNAL OF CANCER, 2007, 97 (08) :1139-1145
[6]   Expression of epiregulin and amphiregulin and K-ras mutation status predict disease control in metastatic colorectal cancer patients treated with cetuximab [J].
Khambata-Ford, Shirin ;
Garrett, Christopher R. ;
Meropol, Neal J. ;
Basik, Mark ;
Harbison, Christopher T. ;
Wu, Shujian ;
Wong, Tai W. ;
Huang, Xin ;
Takimoto, Chris H. ;
Godwin, Andrew K. ;
Tan, Benjamin R. ;
Krishnamurthi, Smitha S. ;
Burris, Howard A., III ;
Poplin, Elizabeth A. ;
Hidalgo, Manuel ;
Baselga, Jose ;
Clark, Edwin A. ;
Mauro, David J. .
JOURNAL OF CLINICAL ONCOLOGY, 2007, 25 (22) :3230-3237
[7]   KRAS mutation status is predictive of response to cetuximab therapy in colorectal cancer [J].
Lièvre, A ;
Bachet, JB ;
Le Corre, D ;
Boige, V ;
Landi, B ;
Emile, JF ;
Côté, JF ;
Tomasic, G ;
Penna, C ;
Ducreux, M ;
Rougier, P ;
Penault-Llorca, F ;
Laurent-Puig, P .
CANCER RESEARCH, 2006, 66 (08) :3992-3995
[8]   KRAS mutations as an independent prognostic factor in patients with advanced colorectal cancer treated with cetuximab [J].
Lievre, Astrid ;
Bachet, Jean-Baptiste ;
Boige, Valerie ;
Cayre, Anne ;
Le Corre, Delphine ;
Buc, Emmanuel ;
Ychou, Marc ;
Bouche, Olivier ;
Landi, Bruno ;
Louvet, Christophe ;
Andre, Thierry ;
Bibeau, Frederic ;
Diebold, Marie-Daniele ;
Rougier, Philippe ;
Ducreux, Michel ;
Tomasic, Gorana ;
Emile, Jean-Francois ;
Penault-Llorca, Frederique ;
Laurent-Puig, Pierre .
JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (03) :374-379
[9]   Correlation between hypermethylation of the RASSF2A promoter and K-ras/BRAF mutations in microsatellite-stable colorectal cancers [J].
Park, Hye-Won ;
Kang, Hio Chung ;
Kim, Il-Jin ;
Jang, Sang-Geun ;
Kim, Kun ;
Yoon, Hyun-Ju ;
Jeong, Seung-Yong ;
Park, Jae-Gahb .
INTERNATIONAL JOURNAL OF CANCER, 2007, 120 (01) :7-12