Bile acids, fibre and colon cancer: the story unfolds

被引：37

作者：

Chaplin, MF ^{[1
]}

机构：

[1] S Bank Univ, Ctr Food Res, London SE1 0AA, England

来源：

JOURNAL OF THE ROYAL SOCIETY OF HEALTH | 1998年 / 118卷 / 01期

关键词：

bile acids; colorectal cancer; dietary fibre; gut flora;

D O I：

10.1177/146642409811800111

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Are the changes in faecal bile acid concentrations the cause of colorectal cancer or one of its effects! This is an area of controversy mainly due to the lack of a clear explanation as to how the bile acid concentrations are controlled under different circumstances. This review presents an outline of the evidence that bile acids are both a causal factor in colorectal cancer and that their concentrations are affected by it in a synergistic manner. It also offers an explanation of how some dietary fibre protects against colorectal cancer.

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页码：53 / 61

页数：9

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