Regulation of the expression of the cold shock proteins CspB and CspC in Bacillus subtilis

被引:25
作者
Kaan, T [1 ]
Jürgen, B [1 ]
Schweder, T [1 ]
机构
[1] Ernst Moritz Arndt Univ Greifswald, Inst Mikrobiol & Mol Biol, D-17487 Greifswald, Germany
来源
MOLECULAR AND GENERAL GENETICS | 1999年 / 262卷 / 02期
关键词
Bacillus subtilis; cold shock; cspB; cspC; mRNA stability;
D O I
10.1007/s004380051093
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The small acidic proteins CspB and CspC are the major cold shock-induced proteins of Bacillus subtilis. Analysis of mRNA revealed a transient four-fold increase in the transcription level of both genes during cold shock. The cspB and cspC mRNAs are dramatically stabilised after a temperature downshift from 37 degrees C to 15 degrees C. The data in this study support the idea that the expression of CspB and CspC in B. subtilis during cold shock is regulated mainly at the post-transcriptional level, as is also the case with CspA in Escherichia coli.
引用
收藏
页码:351 / 354
页数:4
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