Antifungal principles from Piper fulvescens

被引：31

作者：

Freixa, B

Vila, R

Ferro, EA

Adzet, T

Cañigueral, S

机构：

[1] Univ Barcelona, Fac Farm, Unitat Farmacol & Farmacognosia, E-08028 Barcelona, Spain

[2] Univ Asuncion, Fac Ciencias Quim, Asuncion, Paraguay

来源：

PLANTA MEDICA | 2001年 / 67卷 / 09期

关键词：

D O I：

10.1055/s-2001-18838

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

Activity-guided fractionation of the dichloromethane extract from leaves of Piper fulvescens, using an agar overlay bioautographic method, led to the isolation of three antifungal neolignans; identified as conocarpan, eupomatenoid 5 and eupomatenoid 6. The minimal inhibitory concentration of these three neolignans, against five fungi strains were determined. Conocarpan showed the widest activity, whereas eupomatenoid 6 was the most active against dermatophytes.

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收藏

页码：873 / 875

页数：3

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