Oscillatory pallidal local field potential activity correlates with involuntary EMG in dystonia

被引：73

作者：

Chen, CC

Kühn, AA

Hoffmann, KT

Kupsch, A

Schneider, GH

Trottenberg, T

Krauss, JK

Wöhrle, JC

Bardinet, E

Yelnik, J

Brown, P

机构：

[1] Inst Neurol, Sobell Dept Motor Neurosci & Movement Disorders, London WC1N 3BG, England

[2] Chang Gung Mem Hosp & Univ, Dept Neurol, Taipei, Taiwan

[3] Univ Med Berlin, Dept Neurol, Charite, Berlin, Germany

[4] Univ Med Berlin, Dept Radiol, Charite, Berlin, Germany

[5] Univ Med Berlin, Dept Neurosurg, Charite, Berlin, Germany

[6] Univ Hosp Mannheim, Dept Neurosurg, Klinikum Mannheim, Mannheim, Germany

[7] Univ Hosp Mannheim, Dept Neurol, Klinikum Mannheim, Mannheim, Germany

[8] Hop La Pitie Salpetriere, INSERM, Paris, France

[9] CNRS, UPR 640, Paris, France

来源：

NEUROLOGY | 2006年 / 66卷 / 03期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1212/01.wnl.0000196470.00165.7d

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The pathophysiology of dystonia is unclear. The authors recorded local field potentials (LFPs) from deep brain stimulation electrodes implanted in the pallidum of 13 dystonic patients. LFP power correlated with the level of dystonic EMG in the sternocleidomastoid, with maximal positive correlations at the lower contacts of pallidal electrodes. The data suggest that the neuronal synchronization indexed by LFP oscillations in the globus pallidus may be mechanistically linked to dystonic EMG activity.

引用

页码：418 / 420

页数：3

共 9 条

[1] Deep brain stimulation for generalised dystonia and spasmodic torticollis [J].