Graphene oxide-Fe3O4 magnetic nanocomposites with peroxidase-like activity for colorimetric detection of glucose

被引：488

作者：

Dong, Ya-lei ^{[1
,2
]}

Zhang, Hui-ge ^{[1
,2
]}

Rahman, Zia Ur ^{[1
,2
]}

Su, Li ^{[1
,2
]}

Chen, Xiao-jiao ^{[1
,2
]}

Hu, Jing ^{[1
,2
]}

Chen, Xing-guo ^{[1
,2
,3
]}

机构：

[1] Lanzhou Univ, Natl Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China

[2] Lanzhou Univ, Dept Chem & Chem Engn, Lanzhou 730000, Peoples R China

[3] Key Lab Nonferrous Met Chem & Resources Utilizat, Lanzhou 730000, Peoples R China

来源：

NANOSCALE | 2012年 / 4卷 / 13期

基金：

中国国家自然科学基金;

关键词：

CATALYTIC-ACTIVITY; HYDROGEN-PEROXIDE; NANOPARTICLES; OXIDE; HEMIN; BIOCATALYSIS; MIMETICS; POLYMER; H2O2;

D O I：

10.1039/c2nr12109c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In this report, graphene oxide-Fe3O4 magnetic nanocomposites were demonstrated to possess intrinsic peroxidase-like activity and enhanced affinity toward H2O2. The nanocomposites retain their magnetic properties and can be effectively separated by a magnet. Significantly, they were proved to be novel peroxidase mimetics which could quickly catalyze oxidation of the peroxidase substrate 3,3,5,5-tetramethylbenzidine (TMB) in the presence of H2O2, producing a blue-colored solution. Kinetic analysis indicates that the catalytic behavior is in accord with typical Michaelis-Menten kinetics and follows a ping-pong mechanism. On the basis of the high activity, the reaction provides a simple, sensitive and selective method for colorimetric detection of glucose in diabetic urine.

引用

页码：3969 / 3976

页数：8

共 39 条

[1] V2O5 Nanowires with an Intrinsic Peroxidase-Like Activity [J].

Andre, Rute ;

Natalio, Filipe ;

Humanes, Madalena ;

Leppin, Jana ;

Heinze, Katja ;

Wever, Ron ;

Schroeder, H. -C. ;

Mueller, Werner E. G. ;

Tremel, Wolfgang .

ADVANCED FUNCTIONAL MATERIALS, 2011, 21 (03) :501-509

[2] Oxidase-Like Activity of Polymer-Coated Cerium Oxide Nanoparticles [J].

Asati, Atul ;

Santra, Santimukul ;

Kaittanis, Charalambos ;

Nath, Sudip ;

Perez, J. Manuel .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2009, 48 (13) :2308-2312

[3] POLYOL RECOGNITION BY A STEROID-CAPPED PORPHYRIN - ENHANCEMENT AND MODULATION OF MISFIT GUEST BINDING BY ADDED WATER OR METHANOL [J].

BONARLAW, RP ;

SANDERS, JKM .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1995, 117 (01) :259-271

[4] Helical Carbon Nanotubes: Intrinsic Peroxidase Catalytic Activity and Its Application for Biocatalysis and Biosensing [J].

Cui, Rongjing ;

Han, Zhida ;

Zhu, Jun-Jie .

CHEMISTRY-A EUROPEAN JOURNAL, 2011, 17 (34) :9377-9384

[5] Nanostructured FeS as a Mimic Peroxidase for Biocatalysis and Biosensing [J].

Dai, Zhihui ;

Liu, Shaohua ;

Bao, Jianchun ;

Jui, Huangxian .

CHEMISTRY-A EUROPEAN JOURNAL, 2009, 15 (17) :4321-4326

[6] Multifunctional Mesoporous Composite Microspheres with Well-Designed Nanostructure: A Highly Integrated Catalyst System [J].

Deng, Yonghui ;

Cai, Yue ;

Sun, Zhenkun ;

Liu, Jia ;

Liu, Chong ;

Wei, Jing ;

Li, Wei ;

Liu, Chang ;

Wang, Yao ;

Zhao, Dongyuan .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2010, 132 (24) :8466-8473

[7]

Fromm H. J., 2012, BIOCHEMISTRY-US, P108

[8] Covalent hemin-DNA adducts for generating a novel class of artificial heme enzymes [J].

Fruk, L ;

Niemeyer, CM .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2005, 44 (17) :2603-2606

[9] Magnetite Nanoparticle-Linked Immunosorbent Assay [J].

Gao, Lizeng ;

Wu, Jiamin ;

Lyle, Sarah ;

Zehr, Keith ;

Cao, Liangliang ;

Gao, Di .

JOURNAL OF PHYSICAL CHEMISTRY C, 2008, 112 (44) :17357-17361

[10] Intrinsic peroxidase-like activity of ferromagnetic nanoparticles [J].

Gao, Lizeng ;

Zhuang, Jie ;

Nie, Leng ;

Zhang, Jinbin ;

Zhang, Yu ;

Gu, Ning ;

Wang, Taihong ;

Feng, Jing ;

Yang, Dongling ;

Perrett, Sarah ;

Yan, Xiyun .

NATURE NANOTECHNOLOGY, 2007, 2 (09) :577-583

← 1 2 3 4 →