Palladium-catalysed in situ zipper generation-cyclisation-anion capture. Synthesis of 3,3-disubstituted indolines and 2,3-dihydrobenzofurans

被引：25

作者：

Grigg, R ^{[1
]}

Mariani, E ^{[1
]}

Sridharan, V ^{[1
]}

机构：

[1] Univ Leeds, Sch Chem, Mol Innovat Divers & Automated Synth Ctr MIDAS, Leeds LS2 9JT, W Yorkshire, England

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 49期

关键词：

D O I：

10.1016/S0040-4039(01)01811-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A palladium-catalysed one-pot reaction for the in situ assembly of monocyclisation 'zippers' and subsequent cyclisation-anion capture with aryl/heteroaryl boronic acids produces 3,3-disubstituted indolines and 2,3-dihydrobenzofurans. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：8677 / 8680

页数：4

共 7 条

[1] One-step palladium-catalyzed synthesis of substituted dihydrofurans from the carbonate derivatives of γ-hydroxy-α,β-unsaturated sulfones [J].

Garrido, JL ;

Alonso, I ;

Carretero, JC .

JOURNAL OF ORGANIC CHEMISTRY, 1998, 63 (25) :9406-9413

[2] Palladium catalysed cascade cyclisation-anion capture, relay switches and molecular queues [J].

Grigg, R ;

Sridharan, V .

JOURNAL OF ORGANOMETALLIC CHEMISTRY, 1999, 576 (1-2) :65-87

[3] Heterocycles via Pd catalysed molecular queuing processes. Relay switches and the maximisation of molecular complexity [J].

Grigg, R ;

Sridharan, V .

PURE AND APPLIED CHEMISTRY, 1998, 70 (05) :1047-1057

[4] Palladium catalysed tandem cyclisation-anion capture processes .3. Organoboron anion transfer agents [J].

Grigg, R ;

Sansano, JM ;

Santhakumar, V ;

Sridharan, V ;

Thangavelanthum, R ;

ThorntonPett, M ;

Wilson, D .

TETRAHEDRON, 1997, 53 (34) :11803-11826

[5]

LA CW, 2000, ORG LETT, V9, P1213

[6]

NAMOTO H, 1997, J ORG CHEM, V19, P6450

[7] A novel palladium-mediated cascade reaction triggered by strain release of the cyclobutane system. A new general route to benzo- and naphthohydrindans [J].

Nemoto, H ;

Miyata, J ;

Yoshida, M ;

Raku, N ;

Fukumoto, K .

JOURNAL OF ORGANIC CHEMISTRY, 1997, 62 (22) :7850-7857

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