Metabolic phenotyping in health and disease

被引:669
作者
Holmes, Elaine [1 ]
Wilson, Ian D. [2 ]
Nicholson, Jeremy K. [1 ]
机构
[1] Univ London Imperial Coll Sci Technol & Med, Fac Med, Div Surg Oncol Reprod Biol & Anaesthet, Dept Biomol Med, London SW7 2AZ, England
[2] AstraZeneca, Dept Safety Med, Macclesfield SK10 4TG, Cheshire, England
关键词
D O I
10.1016/j.cell.2008.08.026
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Analyzing metabolites (small molecules <1 kDa) in body fluids such as urine and plasma using various spectroscopic methods provides information on the metabotype (metabolic phenotype) of individuals or populations, information that can be applied to personalized medicine or public healthcare.
引用
收藏
页码:714 / 717
页数:4
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