Nucleotide sequences and further characterization of human papillomavirus DNA present in the CaSki, SiHa and HeLa cervical carcinoma cell lines

被引：164

作者：

Meissner, JD ^{[1
]}

机构：

[1] Ctr Dis Control & Prevent, Human Papillomavirus Sect, Natl Ctr Infect Dis, Publ Hlth Serv,US Dept Hlth & Human Serv, Atlanta, GA 30333 USA

来源：

JOURNAL OF GENERAL VIROLOGY | 1999年 / 80卷

关键词：

D O I：

10.1099/0022-1317-80-7-1725

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The complete nucleotide sequences of the human papillomavirus type 16 (HPV-16) variants present in the CaSki and SiHa cervical carcinoma cell lines and the primary subgenomic HPV-18 variant present in the HeLa cervical carcinoma cell line were determined using overlapping bulk PCR products as templates. PCR-based methods were also used to characterize five previously unreported CaSki HPV-16 genomic disruptions and the 5' cellular-viral junction common to all HeLa HPV-18 subgenomic structures.

引用

页码：1725 / 1733

页数：9

共 61 条

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