Smaller volume of anterior cingulate cortex in abuse-related posttraumatic stress disorder

被引：114

作者：

Kitayama, N

Quinn, S

Bremner, JD

机构：

[1] NIMH, Div Adult Mental Hlth, Natl Ctr Neurol & Psychiat, Kodaira, Tokyo 1878553, Japan

[2] Dept Psychiat Radiol, Atlanta, GA USA

[3] Emory Ctr Positron Emiss Tomog, Atlanta, GA USA

[4] Atlanta VAMC, Decatur, GA USA

来源：

JOURNAL OF AFFECTIVE DISORDERS | 2006年 / 90卷 / 2-3期

关键词：

posttraumatic stress disorder; anterior cingulate; magnetic resonance; volumetry; Brodmann's area;

D O I：

10.1016/j.jad.2005.11.006

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Objective: The anterior cingulate cortex (ACC) plays an important role in emotion, and studies in animals have shown changes in ACC structure with early life stress. The purpose of this study was to measure volume of the ACC in PTSD. Method: Magnetic resonance imaging (MRI) was used to measure ACC volume in 8 subjects with abuse-related PTSD and 13 healthy subjects without PTSD. ACC volume included Brodmann's area [BA] 24 and 32. Results: Right ACC volume in PTSD patients was significantly smaller than in non-PTSD subjects. Conclusion: These results are consistent with smaller ACC volume in PTSD. (c) 2005 Elsevier B.V. All rights reserved.

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页码：171 / 174

页数：4

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