The transcellular railway: insights into leukocyte diapedesis

被引:36
作者
Dejana, E [1 ]
机构
[1] Univ Milan, Fac Sci, Dept Biomol Sci & Biotechnol, Milan, Italy
[2] FIRC, Inst Mol Oncol, Milan, Italy
关键词
D O I
10.1038/ncb0206-105
中图分类号
Q2 [细胞生物学];
学科分类号
071009 [细胞生物学]; 090102 [作物遗传育种];
摘要
Leukocyte recruitment from blood to areas of infection is a key step in both innate and adaptive immunological responses. The predominant model has been that leukocytes transmigrate through the junctions between adjacent endothelial cells. However, leukocytes can also migrate through the endothelial cells, and new insights suggest that both caveolae and intermediate filaments are important for this. © 2006 Nature Publishing Group.
引用
收藏
页码:105 / 107
页数:3
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