Role of gamma interferon in controlling murine chlamydial genital tract infection

被引：60

作者：

Ito, JI ^{[1
]}

Lyons, JM ^{[1
]}

机构：

[1] City Hope Natl Med Ctr, Dept Infect Dis, Duarte, CA 91010 USA

来源：

INFECTION AND IMMUNITY | 1999年 / 67卷 / 10期

关键词：

D O I：

10.1128/IAI.67.10.5518-5521.1999

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Earlier investigations have not shown an important role for gamma interferon (IFN-gamma) in the early clearance of chlamydial infection from the murine female genital tract. In a model using a human genital isolate of Chlamydia trachomatis in IFN-gamma and IFN-gamma receptor knockout mice, we were able to demonstrate a major role for IFN-gamma in mediating control of infection throughout the course of infection.

引用

页码：5518 / 5521

页数：4

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