Novel highly substituted bisaryl ethers, phomosines D-G, isolated from the endophytic fungus Phomopsis sp from Adenocarpus foliolosus

被引：26

作者：

Dai, JQ

Krohn, K

Flörke, U

Gehle, D

Aust, HJ

Draeger, S

Schulz, B

Rheinheimer, J

机构：

[1] Univ Gesamthsch Paderborn, Dept Chem, D-33098 Paderborn, Germany

[2] Tech Univ Carolo Wilhelmina Braunschweig, Inst Mikrobiol, D-31806 Braunschweig, Germany

[3] BASF AG, D-67056 Ludwigshafen, Germany

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2005年 / 2005卷 / 23期

关键词：

fungal secondary metabolites; phomosines D-G; biraryl ethers; Phomopsis sp; X-ray single crystal analysis; structural elucidation; fungal endophyte;

D O I：

10.1002/ejoc.200500471

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Six new metabolites, phomosines D-G (4-7), 6-hydroxy-6-isopropylcyclohex-1-enecarboxylic acid (8) and (1aS,3R,4R,4aR,6S,7R,8aS)-7-chloro-3,6-dihydroxy-3,4a,8,8-tetramethyl-octahydro-1aH-naphtho[1-b]oxirene-4-carboxylic acid (9) were isolated together with seven known compounds (1-3, 10-13) from the endophytic fungus Phomopsis sp. The structures of 1-13 were determined by spectroscopic methods (mainly extensive 1D and 2D NMR experiments and by mass spectrometric measurements). The antibacterial, fungicidal, and herbicidal properties of the new compounds were evaluated. (c) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005.

引用

页码：5100 / 5105

页数：6

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